‘ The study of more than 700 people focused on the AKT1 gene. It’s involved in dopamine signaling, which is known to be abnormal in psychosis. Dopamine is a neurotransmitter that plays an important role in mental health.
‘ “We found that cannabis users who carry a particular variant in the AKT1 gene had a twofold increased probability of a psychotic disorder and this increased up to sevenfold if they used cannabis daily,” wrote Dr. Marta Di Forti, of King’s College London’s Institute of Psychiatry in England, and colleagues. “Our findings help to explain why one cannabis user develops psychosis while his friends continue smoking without problems.” ‘